Job search

So, like Kil, I may lose my job in the near future (April to be more exact) - the college I work with may choose not to renew the contract my company has with them. I've been thinking about it a lot lately, since one of my colleagues is driving me bonkers and it is a escape mechanism for me to dream of a future of which he is not a part.
But what would I do? My life has taken so many twists and turns that I have experienced many different job paths. I am not living up to my potential, but do not know how to get there (I believe my potential includes winning a Nobel Prize. I have a lot of work ahead of me).